Author Correction Issued for Tuberous Sclerosis Research Paper
Nature publishes formal corrections regarding figure panels and data labeling in mTORC1 study.
1Formal Correction Published
The original research article titled mTORC1 drives cell-autonomous astrocyte reactivity in tuberous sclerosis, published on 23 September 2026, has undergone a formal author correction. This update addresses specific inaccuracies identified within the figures and captions of the study. These changes are now reflected in both the HTML and PDF versions of the paper.
2Figure Panel Duplication
The primary visual error occurred in Figure 3n, where the bottom-right panel was identified as a duplicate of the panel located to its immediate left. This correction rectifies the visual representation of the data, ensuring that the intended experimental results are accurately displayed for readers and researchers reviewing the study's findings on astrocyte reactivity.
3Caption Designation Transposition
In the Extended Data Figure 3 caption, the researchers identified that the designations for cluster 1 and cluster 2 were transposed in the description of panel h. This error in labeling could have potentially misled interpretation of the cluster-specific data, necessitating this formal correction to maintain the integrity of the published scientific record.
4Data Labeling Adjustment
A specific labeling error was corrected in Extended Data Figure 10c. The label that previously read Tuber 29 has been updated to Tuber 26. Such precise adjustments are critical in neuroscientific research to ensure that individual samples or subjects are correctly identified and tracked throughout the complex data analysis process presented in the study.
5Institutional Research Collaboration
The research involved a multi-institutional effort led by authors from the University of California, Berkeley, and Stanford University. Key contributors include Thomas L. Li, John D. Blair, Taesun Yoo, Dirk Hockemeyer, and Helen S. Bateup. Their work spans departments including Molecular and Cell Biology, Neuroscience, and Neurosurgery, highlighting the interdisciplinary nature of the tuberous sclerosis study.
6Open Access Compliance
The article is published under an open access license, allowing for broad dissemination of the findings. Readers are encouraged to consult the Copyright Information section for specific details regarding permitted re-use of the content. For any usage exceeding these permissions, the Rights and Permissions team remains the primary point of contact for formal inquiries.
7Scientific Integrity Standards
The issuance of this correction reflects standard academic practices for maintaining transparency in high-impact journals like Nature. By addressing minor figure and labeling errors promptly, the authors ensure that the scientific community can rely on the accuracy of the data presented. This process is essential for the ongoing validation of complex molecular biology research.
8Impact on Future Research
Accurate reporting in studies concerning mTORC1 and astrocyte reactivity is vital for understanding tuberous sclerosis pathology. These corrections ensure that future researchers building upon this work utilize the correct data points and figure interpretations. Maintaining such rigorous standards is fundamental to the advancement of neurological science and the development of potential future clinical interventions.
Original article: Nature — Author Correction Issued for Tuberous Sclerosis Research Paper