# Revisiting the Extreme Male Brain Theory in Modern Autism Research Simon Baron-Cohen reflects on the evolution of autism diagnostic frameworks and gender dynamics. - **Source:** [New Scientist](https://www.newscientist.com/) - **Published:** 2026-10-20 - **Original article:** - **On Brifing:** https://brifing.si/s/4448ecf7-a372-4656-b004-b414ee3dfa70 ## Shifting Diagnostic Landscapes Autism diagnoses have increased tenfold over recent decades, driven by broader diagnostic criteria and increased public awareness. While early pop culture stereotypes like Rain Man dominated perceptions, modern representations now include diverse figures such as Astrid Nielsen. This evolution reflects a significant shift in how society identifies and understands neurodivergent individuals today. ## The Extreme Male Brain In the early 2000s, researcher Simon Baron-Cohen proposed the extreme male brain theory, linking autism to high systematic thinking and low empathy. This concept was rooted in his 1990s observations of autistic children. While influential, the label has faced substantial criticism for potentially reinforcing gender stereotypes and misrepresenting the condition's complexity. ## Refining Empathy Definitions Baron-Cohen distinguishes between cognitive empathy, which involves recognizing thoughts, and affective empathy, which involves emotional responses. Autistic individuals often struggle with cognitive empathy but may possess heightened affective empathy. This framework challenges the misconception that autism equates to a total lack of empathy, contrasting it with the profile of psychopathy. ## Systemising as a Core Trait The systemising concept describes a natural drive to analyze and construct rule-governed systems, akin to a spider spinning a web. Baron-Cohen suggests this cognitive architecture is distinct from social navigation. Historically, figures like Isaac Newton are cited as potential examples of this profile, characterized by obsessive interests and social difficulties. ## Psychometric Testing Frameworks Baron-Cohen developed psychometric tests to measure empathising and systemising abilities across populations. These tests consistently show that autistic individuals cluster in specific regions of the graph. While he initially linked these findings to an extreme male profile, he emphasizes that these are statistical patterns rather than absolute rules for every individual. ## Gender Ratio Disparities The male-to-female autism diagnosis ratio has dropped from 4:1 to 3:1 in children under ten over the last two decades. Some researchers argue that male-centric diagnostic criteria previously caused systemic underdiagnosis in women. Baron-Cohen suggests social pressures to mask symptoms likely contribute significantly to these historical gaps in identification and support. ## Prenatal Hormone Influence Research into prenatal sex steroid theory suggests that fetal exposure to sex hormones may influence brain architecture and autistic traits. Studies on brain tissue organoids indicate that hormone exposure levels can alter development. Baron-Cohen notes that while these biological factors are relevant, they interact complexly with genetics and environmental influences. ## Non-Binary and Diverse Profiles Recent data indicates that non-binary individuals are 5.5 times more likely to be autistic, challenging the traditional binary view of sex and gender. Baron-Cohen acknowledges that the empathising-systemising framework is not an exclusive definition. He emphasizes that sensory sensitivity, IQ, and executive function are also critical dimensions that require further research. ## The Rise of Subtyping Researchers are increasingly moving toward identifying distinct autism subtypes based on genetic patterns and brain activity. In Sweden, diagnoses rose tenfold between 2000 and 2022, highlighting the need for more granular definitions. Subtyping is considered urgent to provide tailored support and improve the quality of life for diverse autistic communities globally. ## Ethical Research Priorities The Autism Research Centre at the University of Cambridge explicitly avoids seeking a cure or developing prenatal tests for autism. Their core mission focuses on involving autistic people in study designs to ensure research serves their actual needs. This approach aims to address community fears regarding the potential misuse of diagnostic subtyping. ## Moving Beyond Labels Baron-Cohen has rolled back the use of the extreme male brain label, calling it unhelpful despite standing by his core empathising-systemising framework. He maintains that understanding these cognitive dimensions remains scientifically valid. The focus is now on integrating these findings into a broader, more inclusive understanding of neurodiversity and human variation. ## Future Research Directions The field of autism research is currently at a crossroads, balancing the need for simplified definitions with the reality of biological complexity. Future progress depends on identifying common threads across subtypes while respecting individual differences. Ultimately, the goal remains to provide better quality of life through evidence-based, community-centered scientific inquiry. ## Sources covering this story - https://www.newscientist.com/article/2592226-where-does-the-extreme-male-brain-sit-in-our-better-understanding-of-autism/?utm_campaign=RSS|NSNS&utm_content=home&utm_medium=RSS&utm_source=NSNS — --- _Summary written by Brifing from the original reporting. Copyright in the original article belongs to its publisher; read the full piece at the link above._