# Researchers Create First 'Planimals' via Cellular Fusion Scientists fused primitive algae with animal cells to explore future pharmaceutical production potential. - **Source:** [Jiji Press](https://www.jiji.com) - **Published:** 2026-11-12 - **Topic:** [science](https://brifing.si/c/science) - **Original article:** - **On Brifing:** https://brifing.si/s/79f2158c-93c0-40fa-93d6-ef3abe8c1fd7 ## Successful Cellular Hybridization Researchers at the University of Tokyo have successfully created the first 'planimal' cells. This unique biological entity was formed by fusing primitive algae known as Cyanidioschyzon merolae with cultured hamster cells. The experiment marks a significant milestone in synthetic biology, demonstrating that disparate cellular structures can be integrated into a single functional unit. ## Structural Fusion Process The fusion process involved combining the green, microscopic algae with standard hamster cells used in pharmaceutical manufacturing. During this integration, the chloroplasts within the algae were systematically broken down. Consequently, the resulting hybrid cells are unable to perform photosynthesis, focusing instead on the structural and metabolic integration of the two distinct parent cell types. ## Role of Hamster Cells The choice of hamster cells is strategic, as these are industry standards for producing complex medical proteins. By integrating algal components into these established production platforms, scientists aim to create more efficient biological factories. This approach leverages the robust growth characteristics of animal cells while exploring the unique genetic contributions of primitive algae. ## Future Industrial Applications The primary goal of this research is to utilize these hybrid cells for the production of useful substances. By modifying the cellular machinery, the team hopes to synthesize pharmaceuticals or industrial chemicals more effectively. This innovation could eventually transform how biological materials are manufactured, offering a new pathway for advanced biotechnology and medical research. ## Limitations of Current Hybrids While the fusion was successful, the current planimal cells do not retain the photosynthetic capabilities of their algal ancestors. The degradation of chloroplasts during the fusion process limits the cells' metabolic pathways. Future studies will need to address whether these organelles can be preserved or if other algal traits can be successfully expressed. ## Significance of Primitive Algae Cyanidioschyzon merolae is a highly primitive form of red algae often used in laboratory settings due to its simple cellular structure. Its inclusion in this experiment provides a baseline for understanding how ancient evolutionary traits can be merged with modern mammalian cells. This provides a unique model for studying cellular compatibility and genetic expression. ## Advancing Synthetic Biology This development represents a shift in synthetic biology, moving beyond simple genetic modification toward the creation of entirely new cellular architectures. By merging different kingdoms of life, researchers are testing the boundaries of what is biologically possible. This methodology could open doors to creating organisms with entirely new functions for various scientific sectors. ## Next Research Milestones The research team, led by Professor Yukihiro Matsunaga, continues to analyze the stability and functionality of these hybrid cells. The next phase will focus on determining if these cells can maintain long-term viability in culture. Establishing stable, reproducible lines will be essential before these planimals can be deployed for any real-world pharmaceutical production. ## Sources covering this story - https://www.jiji.com/jc/article?k=2026111200953&g=soc&m=rss — --- _Summary written by Brifing from the original reporting. Copyright in the original article belongs to its publisher; read the full piece at the link above._