# Correction Published for Molecular Biology Study in Nature Journal URB1 protein's critical role in rRNA processing study receives published correction. - **Source:** [Nature](https://brifing.si/source/4d850c3b-dd79-4024-bc91-db2571889199) - **Published:** 2026-08-10 - **Topic:** [Business](https://brifing.si/c/business) - **Original article:** - **On Brifing:** https://brifing.si/s/98aa71ea-cea9-4e8d-a08f-8aff05535897 ## Scientific publication correction process A molecular biology study published in Nature on March 8, 2023, examining the role of URB1 protein in rRNA processing, was found to contain data duplication errors. The team of Chinese scientists corrected repeated data errors in Figure 2c's NIP7 URB1-KD and DDX31 scramble profiles. Additionally, primer sequences in Supplementary Table 1 required updates for POLR1D-F and POLR1D-R entries that were incorrectly duplicated from POLR1C-F data. ## Technical details corrected Researchers explained that POLR1C-F data was mistakenly repeated as POLR1D-F and POLR1D-R in the original study. The correction was implemented in both HTML and PDF versions of the article. For comparison purposes, original Figure 2 was provided as supplementary information alongside this correction notice. The study bears signatures of 15 researchers from Shanghai Institute of Biochemistry and Cell Biology. ## Study's original contribution The research revealing URB1 protein's critical role in nucleolar removal of 3' ETS rRNA sheds light on molecular mechanisms preventing exosome surveillance. Conducted at Chinese Academy of Sciences' Center for Excellence in Molecular Cell Science, the study included participants from ShanghaiTech University and Tsinghua University, representing a collaborative effort across leading Chinese research institutions. ## Interdisciplinary collaboration The project brought together scientists from six prominent Chinese research institutions. Researchers from Howard Hughes Medical Institute and UT Southwestern Medical Center also contributed. Positioned at the intersection of molecular biology, biophysics and computational biology, the study advances understanding of complex cellular processes through cutting-edge methodologies. ## Scientific publishing standards Errors in studies published by prestigious journals like Nature are transparently addressed through correction notices, maintaining data integrity in scientific literature. The correction notice is accessible through Springer Nature's SharedIt content-sharing initiative, demonstrating commitment to open scientific communication and rigorous publishing standards. ## Methodological aspects Cryo-EM techniques employed in the study were conducted at Tsinghua University's Technology Center for Protein Sciences. Researchers from Fudan University's Shanghai Key Laboratory of Medical Epigenetics contributed to elucidating molecular mechanisms. The project highlights the importance of international collaborations in driving scientific progress across specialized research domains. ## Transparency in scientific communication Correction notices play vital roles in maintaining accuracy in scientific literature and ensuring proper dissemination of knowledge. Researchers subscribed to Nature Briefing newsletter receive updates about such corrections. The corrected version remains accessible through the study's DOI number, supporting ongoing scientific discourse and reference. ## Advances in molecular biology The discovery and functional analysis of URB1 protein provides new insights into cellular regulation mechanisms. These findings may contribute to understanding molecular bases of cancer and other diseases. Such research from China's leading institutions continues making significant contributions to the global scientific ecosystem through rigorous investigation and collaboration. ## Sources covering this story - https://www.nature.com/articles/s41586-026-10978-7 — --- _Summary written by Brifing from the original reporting. Copyright in the original article belongs to its publisher; read the full piece at the link above._