# The quest to keep organs alive outside the body

Innovative research aims to overcome time limits in organ transplantation

- **Source:** [MIT Technology Review](https://www.technologyreview.com)
- **Published:** 2026-07-24
- **Original article:** <https://www.technologyreview.com/2026/07/24/1140790/the-quest-to-keep-organs-alive-outside-the-body/>
- **On Brifing:** https://brifing.si/s/c4ad2a5a-7d81-422d-b4ef-a0df298b3594

## The time challenge in organ donation

One of the biggest challenges in organ donation is the limited survival time of organs outside the body, often just a few hours. This constraint complicates the transplantation process and hinders the delivery of organs to suitable recipients.

## Supercooling technology

In a recent study, pig kidneys were supercooled and preserved for days. This method allowed the organs to be stored at −4 °C and successfully transplanted, marking a significant milestone in organ preservation.

## The difficulties of cryopreservation

Freezing organs is highly challenging. Ice crystals damage tissues, rendering organs unusable. However, researchers are exploring cryopreservation techniques that keep cells in a glass-like state, offering potential solutions.

## Machine perfusion

Another approach to extending organ lifespan is using machine perfusion devices that mimic conditions inside the body. These devices can preserve livers and kidneys for up to 24 hours, improving transplantation outcomes.

## Hope for eye transplants

Researchers are adapting machine perfusion for eyes, paving the way for whole-eye transplants. This breakthrough holds promise for revolutionizing organ preservation and transplantation.

## The future of organ preservation

Innovations in organ preservation have the potential to transform transplantation processes. These advancements could play a critical role in addressing the global shortage of donor organs.

## Sources covering this story

- https://www.technologyreview.com/2026/07/24/1140790/the-quest-to-keep-organs-alive-outside-the-body/ — 

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_Summary written by Brifing from the original reporting. Copyright in the original article belongs to its publisher; read the full piece at the link above._
