# Maria de Sousa Prize Honors Young Portuguese Health Researchers

Five scientists receive funding for innovative projects in oncology, neurology, and immunology.

- **Source:** [Notícias ao Minuto](https://www.noticiasaominuto.com)
- **Published:** 2026-11-06
- **Topic:** [health](https://brifing.si/c/health)
- **Original article:** <
                https://www.noticiasaominuto.com/lifestyle/3079544/premio-maria-de-sousa-distingue-trabalhos-sobre-cancro-artrite#utm_source=rss-ultima-hora&utm_medium=rss&utm_campaign=rssfeed
                >
- **On Brifing:** https://brifing.si/s/fd6b3fb2-0cc0-4f42-ae33-46b19e862b2c

## Maria de Sousa Prize Overview

The Maria de Sousa Prize, established in 2021, honors the late immunologist Maria de Sousa by supporting young Portuguese researchers. This year, the Bial Foundation and the Portuguese Medical Association awarded five scientists. Each recipient receives up to 30,000 euros to conduct research and undertake internships at prestigious international institutions.

## Smart Wound Dressing Innovation

Luísa Fialho from the University of Porto is developing a color-changing antimicrobial dressing. The material remains yellow during normal healing but turns blue if an infection occurs. It releases regenerative substances gradually, providing a cost-effective alternative to traditional antibiotics by targeting bacteria through multiple fronts without requiring frequent dressing changes.

## Lung Cancer Metastasis Research

Sara Isabel Fernandes of the Flanders Institute of Biotechnology investigates how lung cancer cells reprogram alveolar cells to provide lipids for tumor growth. Building on previous breast cancer findings, she aims to determine if this mechanism applies to non-small cell lung cancer, potentially identifying new therapeutic targets for advanced stage patients.

## Alzheimer's and Brain Lipids

Tatiana Morais from the University of Minho is studying how lipid alterations in astrocytes affect brain function during Alzheimer's disease. By monitoring electrical activity and behavior in mouse models, she seeks to identify novel biomarkers. This research aims to uncover specific molecular changes that could eventually lead to new treatment pathways.

## Neural Mechanisms of Learning

Ana Verónica Domingues explores how the brain adapts behavior based on positive or negative experiences. She focuses on dynorphin, an opioid produced by the brain, and its role in neuron communication. By measuring brain signals during specific stimuli, she aims to clarify how these chemical processes influence learning and behavioral adaptation.

## Nanotechnology in Arthritis Treatment

Simão Teixeira from the International Iberian Nanotechnology Laboratory is researching autoimmune arthritis. He uses 3D-printed joint replicas and magnetic particles to observe how T-lymphocytes react to mechanical forces. This study aims to develop precise treatments that target only the inflammatory cells, minimizing side effects compared to current systemic medication options.

## Institutional Support and Vision

The Bial Foundation, founded in 1994, finances this initiative to encourage the scientific study of human physical and spiritual aspects. The jury, chaired by neuroscientist Rui Costa, selects projects that demonstrate high potential for clinical application. These awards foster international collaboration across research centers in Portugal, Spain, France, and Germany.

## Broader Impact of Research

These diverse projects reflect a commitment to solving complex medical challenges through interdisciplinary approaches. From smart materials to molecular oncology and neurobiology, the research aims to improve patient quality of life. By supporting early-career scientists, the Maria de Sousa Prize ensures a pipeline of innovation for future healthcare advancements.

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_Summary written by Brifing from the original reporting. Copyright in the original article belongs to its publisher; read the full piece at the link above._